WebFeb 8, 2008 · We also analyzed the expression of Cyclins D1, A2, and B1, and phosphorylated Histone H3 and found unexpected expression patterns and cell cycle profiles. The combined utilization of the markers tested and the use of flow cytometry should further facilitate the study of stem and progenitor cell behavior during … WebSep 12, 2012 · Here we report that histone H3 Ser-10 phosphorylation is mediated by the pro-apoptotic kinase protein kinase C (PKC) δ during apoptosis. We observed that PKCδ robustly phosphorylates histone H3 on Ser-10 both in vitro and in vivo. Ectopic expression of catalytically active PKCδ efficiently induces condensed chromatin structure in the nucleus.
Phospho-Histone H3 (Ser10) Antibody (PA5-17869)
WebJan 18, 2024 · Colorectal cancer (CRC) is one of the most frequent gastrointestinal malignancies with high morbidity and mortality rates. Several biological markers for the prognostication of patient outcome of CRCs are available. Recently, our group identified two favorable factors for the survival of CRC patients: PDZ-binding kinase (PBK) and phospho … WebDec 5, 2016 · Phosphorylation of histone H3 at serines 10 or 28 is crucial for chromosome condensation and cell-cycle progression during mitosis and meiosis.11Phosphorylation begins in late G2 phase, is maximal at metaphase, and dephosphorylates at the beginning of telophase.12Because PhH3 expression overlaps with the majority of mitotic phases, and … fish trade supplies ipswich
Adult neurogenesis in songbirds - Wikipedia
WebAs shown, Phospho-Histone H3 (Ser10) Antibody #9701 detects histone H3 phosphorylated on Ser10; however, this antibody does not detect histone H3 phosphorylated on Ser10 … WebSerine 10 of Histone H3 is phosphorylated in association with mitotic chromatin condensation in late G2 and M phase of the cell cycle and thus, PHH3 can distinguish mitosis from apoptotic nuclei. The range of percentage PHH3 positive tumor nuclei was from 0.0 to 6.6% (median value 0.8%). Increased expression of PHH3 WebIn mammalian cells, phosphohistone H3 is negligible during interphase but reaches a maximum for chromatin condensation during mitosis.Immunohistochemical studies showed anti-PHH3 specifically detected the core protein histone H3 only when phosphorylated at serine 10 or serine 28. fish traders