Rs9429505 slc16a1

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August undefined, 2024

WebObjectiveTumor metabolism has always been the focus of cancer research. SLC16A1, as a key factor in catalysis of monocarboxylate transport across the plasma membrane, has been found to be associated with the occurrence and metastasis of a variety of cancers, but its prognostic significance and mechanism in different tumors are still … WebJun 25, 2024 · Erythrocyte Lactate Transporter Defect. In a patient with erythrocyte lactate transporter defect originally reported by Fishbein (1986), Merezhinskaya et al. (2000) identified a heterozygous mutation in the SLC16A1 gene (600682.0001).Two additional patients were found to be heterozygous for another SLC16A1 mutation (600682.0002).All …

Effective October 2024 2037 S505 - Eaton

WebO5A_RS0119590 hypothetical protein [] Gene ID: 24446505, discontinued on 7-Apr-2024. Summary WebMCT1, also known as MOT1, is a multi-pass transmembrane monocarboxylate transporter (MCT) protein, encoded by the gene SLC16A1 (1,2). MCT1 is reported to be expressed in multiple tissues and cell types, including erythrocytes, immune cells, and both cardiac and skeletal myocytes. The primary role of MCT1 is to facilitate proton-coupled ... puzzle jdrama

List of variants in gene SLC16A1 reported as benign for …

WebApr 30, 2024 · SLC16A1, SLC16A3 and SLC16A13 exhibited biomarker potential for prognosis, and we further identified their related genes and regulatory networks, revealing … WebThe SLC16 gene family has fourteen members. Four (SLC16A1, SLC16A3, SLC16A7, and SLC16A8) encode monocarboxylate transporters (MCT1, MCT4, MCT2, and MCT3, … WebOct 3, 2016 · A schematic (a) depicts a region of the endogenous SLC16A1 promoter (−1604, +1045) that was subcloned into a luciferase reporter plasmid. One regulatory region located approximately 624 nt upstream from the SLC16A1 transcription start site (+1) is occupied by dnTCF-1 and contains two putative Wnt response elements (highlighted in … puzzle je m'ennuyais

The SLC16 gene family - structure, role and regulation in health …

Deletion of the diabetes candidate gene - Nature

WebJul 18, 2024 · MCT1, a transmembrane transporter encoded by solute carrier family 16 member 1 ( SLC16A1) gene, transports monocarboxylates, including lactate and ketone bodies ( 7 ). Glycoprotein CD147, also called BSG, is required by MCT1 for proper subcellular expression ( 8, 9 ). WebNM_003051.3(SLC16A1):c.*1942T>C AND Hyperinsulinism, Dominant Clinical significance: Likely benign (Last evaluated: Jun 14, 2016) Review status: 1 star out of maximum of 4 … puzzle javaWebMoreover, SLC16A1 was correlated with the infiltration of immune cells. In conclusion, SLC16A1 is a robust prognostic biomarker for melanoma and may be used as a novel target in immunotherapy. ARTICLE HISTORY Received 12 May 2024 Revised 14 June 2024 Accepted 2 July 2024 ... domaci nasili znaky

"WebUnusually low levels of expression of genes encoding the plasma membrane monocarboxylate transporter, MCT1 (SLC16A1), as well as lactate dehydrogenase A (LDHA) ensure that glucose-derived pyruvate is efficiently metabolized by mitochondria, while exogenous lactate or pyruvate is unable to stimulate metabolism and hence insulin … " - Rs9429505 slc16a1

Rs9429505 slc16a1

hs00240828_ce PCR/Sanger Sequencing Primer pairs

WebProtein Monocarboxylate transporter 1 Gene Slc16a1 Status UniProtKB reviewed (Swiss-Prot) Organism Mus musculus (Mouse) Amino acids 493 Protein existence Evidence at protein level Annotation score 5/5 Entry Feature viewer Publications External links History BLAST Download Add a publication Entry feedback Function WebAnti-SLC16A1 antibody produced in rabbit Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution Synonym (s): Anti-MCT 1, Anti-Monocarboxylate transporter 1, Anti-Solute carrier family 16 member 1 Human Protein Atlas Number: HPA003324 Pricing and availability is not currently available.

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WebList of variants in gene SLC16A1 reported as benign for carbohydrate metabolism disease Included ClinVar conditions (295): Adenosine kinase deficiency; Adult polyglucosan body … WebSLC16A1 (MCT, MCT1) protein expression summary. Proton-coupled monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxy lates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and …

WebJul 1, 2024 · Furthermore, both, Slc16a1 and Slc16a11 show only slight increases in the liver, and although Slc16a11 is stronger dysregulated in the kidney, overexpression of SLC16 transporter in the kidney is ... Web1 hs00240828_ce Affordable TaqMan Assays for All of Your qPCR Needs

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WebSLC16A1 is a member of the SLC family, participating in the transport of lactate, pyruvate, amino acids, ketone bodies, etc. The role of SLC16A1 in tumor immunity has been recently elucidated, while its role in melanoma remains unclear. In this study, bioinformatics analysis was performed to explore the role of SLC16A1 in melanoma. domacin dostava zrenjaninWebSep 22, 2024 · SLC16A1, as a key factor in catalysis of monocarboxylate transport across the plasma membrane, has been found to be associated with the occurrence and metastasis of a variety of cancers, but its prognostic significance and mechanism in different tumors are still unclear. domaćin bas vas zrenjaninWebNM_003051. 4 (SLC16A1): c. *1942T>C rs9429505 0.31497 NM_003051. 4 (SLC16A1): c. *145T>G rs11585690 0.01723 NM_003051. 4 (SLC16A1): c. *332T>C rs41306207 … domacine ozeni se 2022WebApr 12, 2024 · Slc16a1 solute carrier family 16 (monocarboxylic acid transporters), member 1 [ (house mouse)] Gene ID: 20501, updated on 8-Dec-2024 Summary Enables lactate transmembrane transporter activity. Involved in several processes, including behavioral response to nutrient; plasma membrane lactate transport; and regulation of insulin … domaci ng radioWebJun 1, 2024 · Slc16a1 gene belongs to a family of genes that are selectively silenced in mature β-cells as compared to other mammalian cell types and thereby named “β-cell disallowed genes.” Forced expression of Slc16a1 in β-cells interfered with insulin secretion and normal β-cell function. Slc16a1 is previously shown to be regulated by promoter ... domaci nehtove studioWebMonocarboxylate transporter 1 is a ubiquitous protein that in humans is encoded by the SLC16A1 gene (also known as MCT1). [5] [6] [7] It is a proton coupled monocarboxylate … domacini rsWebMar 21, 2024 · SLC16A1-AS1 (SLC16A1 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with SLC16A1-AS1 include Acute Myocardial Infarction and Cervical Cancer . Additional gene information for SLC16A1-AS1 Gene HGNC (49445) NCBI Entrez Gene (100506392) Ensembl (ENSG00000226419) Open Targets … domacini sp u fudbalu